Its Thursday, April 10 and the White Sox (2-9) are in Cleveland to wrap up their series against the Guardians (5-6). Cleveland has pulled out a couple of one-run games through the first two games of the series.
Jonathan Cannon is slated to take the mound for Chicago against Gavin Williams for Cleveland.
Yesterday, Cleveland knocked off the White Sox, 3-2. The Guardians collected just three hits on the day but also were afforded seven walks by the White Sox pitchers. The two combined to provide just enough offense to win the game. One of those hits was Carlos Santana’s second home run of the season.
Lets dive into the matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch White Sox at Guardians
- Date: Thursday, April 10, 2025
- Time: 1:10PM EST
- Site: Progressive Field
- City: Cleveland, OH
- Network/Streaming: CHSN, CLEG
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the White Sox at the Guardians
The latest odds as of Thursday:
- Moneyline: White Sox (+187), Guardians (-227)
- Spread: Guardians -1.5
- Total: 7.0 runs
Probable starting pitchers for White Sox at Guardians
- Pitching matchup for April 10, 2025: Jonathan Cannon vs. Gavin Williams
- White Sox: Jonathan Cannon (0-1, 3.12 ERA)
Last outing: 4/4 at Detroit – 3.2IP, 3ER, 3H, 3BB, 3Ks - Guardians: Gavin Williams (0-0, 4.50 ERA)
Last outing: 4/4 at Angels – 3IP, 2ER, 5H, 3BB, 5Ks
- White Sox: Jonathan Cannon (0-1, 3.12 ERA)
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Top betting trends & insights to know ahead of White Sox at Guardians
- Despite being 2-9, the White Sox are 7-4 on the Run Line this season
- The Guardians have won their last 3 games and 4 of their last 5 against divisional opponents
- The Guardians last 3 games have stayed UNDER the Game Total
- The Guardians have failed to cover the Run Line in 4 straight games
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s game between the White Sox and the Guardians
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Thursday’s game between the White Sox and the Guardians:
- Moneyline: NBC Sports Bet is recommending a play on the Cleveland Guardians on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 7.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
- Drew Dinsick (@whale_capper)
- Vaughn Dalzell (@VmoneySports)
- Brad Thomas (@MrBradThomas)
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