Pistons vs Cavaliers Computer Picks: Our Best Player Prop Projections for Game 6

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The Detroit Pistons saw their season flash right before their eyes after squandering Game 5 against the Cleveland Cavaliers, where our NBA player prop projections have identified several strong value opportunities.

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By breaking down the data and comparing it to the latest market lines, we’ve uncovered where the strongest betting edges lie for this pivotal matchup.

These Pistons vs. Cavaliers predictions are driven by numbers instead of guesswork.

If you’re building your card, here are the model’s top NBA picks for Friday, May 15.

Pistons vs Cavaliers computer picks for Game 6

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Pistons Game 6 computer picks

Cade Cunningham Under 27.5 points (-120)

Projection: 26.47 points

Cade Cunningham erupted for 39 points in Game 5, but the big question heading into a do-or-die Game 6 on the Cleveland Cavaliers home floor is whether he has enough left in the tank.

The Detroit Pistons have been in this spot before, with Cunningham often stepping up under elimination pressure to keep them alive. But if he can’t replicate that production — and falls short of this points prop projection — it could mark the end of Detroit’s season in Cleveland.

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Jalen Duren Over 8.5 rebounds (+105)

Projection: 9.66 rebounds

The Pistons need Jalen Duren to step up on the glass, especially after he’s fallen well short of his rebounds prop in three straight losses. With desperation setting in, Detroit will be leaning on him to reclaim his usual dominance on the boards and help keep their season alive.

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Duncan Robinson Over 2.5 3-pointers (-112)

Projection: 2.95 3-pointers

The Pistons will need Duncan Robinson’s shooting badly in Game 6, especially from beyond the arc. After sitting out Game 5 with back soreness, the veteran sharpshooter appears on track to return following participation in shootaround.

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The injury clearly limited his impact in Game 4, where he finished with just four points and one made three. If he’s not restricted tonight, expect Robinson to find his rhythm again and push past this prop line from deep.

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Cavaliers Game 6 computer picks

James Harden Over 19.5 points (-110)

Projection: 22.65 points

The math is simple: when James Harden is rolling offensively, the Cavaliers usually benefit. The pattern has held throughout the series — his aggressiveness and scoring tend to translate into wins. This points line feels a bit light compared to his ceiling, and it’ll be on Harden to prove it again.

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Evan Mobley Over 8.5 rebounds (+120)

Projection: 9.54 rebounds

The Cavaliers have ranked seventh in offensive rebounding over their last 10 games, and Evan Mobley steps back into focus after a steady, impactful Game 5.

He’s narrowly missed this prop in three straight outings, but with a trip to the Eastern Conference Finals on the line, expect him to bring added urgency on the glass and fight for every rebound against the Pistons.

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Donovan Mitchell Over 3.5 assists (+100)

Projection: 4.65 assists

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After shouldering a major scoring load all series, it’s unrealistic to expect Donovan Mitchell to keep living off tough buckets alone.

He’s consistently hovered around this assists line throughout the matchup, and there’s no better spot to break through than a pivotal Game 6 at home with a chance to advance.

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