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Darlington Raceway is the site of the NASCAR Cup Series Chase opener. The Cook Out Southern 500 at “The Track Too Tough to Tame” is the final Crown Jewel race of the 2026 season. 

Oddsmakers are favoring three Toyota drivers to take the checkered flag on Sunday night. While the odds lean towards the Chase contenders, it is worth looking at some sleepers and longshots to win Darlington. 

NASCAR betting odds for the Cook Out Southern 500 at Darlington

Here is a look at the complete betting odds for Sunday’s Cook Out Southern 500 at Darlington. 

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Denny Hamlin +500

Tyler Reddick +550

Chase Briscoe +650

Kyle Larson +700

Ryan...

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