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There are just two ranked matchups on the Week 10 college football schedule, and one of them comes in the ACC as the No. 20 SMU Mustangs host the No. 18 Pittsburgh Panthers. SMU is 7-1 overall and 3-1 at home, while Pittsburgh is 7-0 overall and 2-0 on the road. SMU quarterback Kevin Jennings and Pitt quarterback Eli Holstein have been dealing with injuries, but they’re both expected to start in this matchup that has College Football Playoff implications. 

Kickoff is 8 p.m. ET at SMU’s Gerald J. Ford Stadium. The Mustangs are favored by 7.5 points in the latest SMU vs. Pittsburgh odds, and the over/under is 56.5 points. Before entering any SMU vs. Pittsburgh picks, you’ll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 16-7 on all top-rated picks over the past five weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.

The model has set its sights on Pitt vs. SMU. You can head to SportsLine to see its picks. Here are several college football betting lines for the SMU vs. Pitt game:

  • SMU vs. Pittsburgh spread: SMU -7.5
  • SMU vs. Pittsburgh over/under: 56.5 points
  • SMU vs. Pittsburgh money line: SMU -288, Pittsburgh +229
  • SMU vs. Pittsburgh picks: See picks here
  • SMU vs. Pittsburgh streaming: FuboTV (Try for free)

What you need to know about SMU

The Mustangs escaped with a 28-27 win over Duke last week, though they failed to cover as 11-point favorites. SMU relied on the efforts of Brashard Smith, who rushed for 117 yards and two touchdowns and Roderick Daniels Jr., who picked up 153 receiving yards and a touchdown. 

After a slower start to the season, the Mustangs have hit their stride in ACC play, going 4-0 straight up and 3-1 against the spread in those contests. Jennings has thrown for 1,594 yards and 10 touchdowns, while adding 321 yards and three scores on the ground. SMU, meanwhile, appears to have the edge on defense since the Mustangs rank fourth in the ACC in both scoring and total defense. See who to back at SportsLine. 

What you need to know about Pittsburgh 

Meanwhile, Pittsburgh handled Syracuse last Thursday 41-13, covering as a 5-point favorite, and then got to enjoy a mini-bye to prepare for this one. The Panthers are 6-1 against the spread this season, and they’ve been clutch in tight games, winning four of their five games against Power Four teams by 10 points or fewer.

Holstein, an Alabama transfer, has thrown for 17 touchdowns and he’s spreading the ball around. Six players have at least 18 receptions, with Konata Mumpfield (27-473-3) leading the way. Desmond Reid (89-541-3) is the team’s top rusher. See who to back at SportsLine.

How to make SMU vs. Pittsburgh picks

The model has simulated SMU vs. Pittsburgh 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits well over 60% of the time. You can only see the pick at SportsLine.

Who wins Pitt vs. SMU, and which side of the spread hits well over 60% of the time? Visit SportsLine now to find out, all from the model that’s on a 16-7 roll on top-rated college football picks.



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