Big Ten meets Mountain West as Penn State hosts Nevada in a 2025 college football Week 1 battle on Saturday on Paramount+. The Nittany Lions were a surprise story last season, finishing 8-1 in the Big Ten and 13-3 overall as they made it all the way to the College Football Playoff semifinals before falling to Notre Dame. Meanwhile, the Wolf Pack brought up the rear in the Mountain West, going 3-10 overall and dropping six straight to end their 2024 campaign.
Kickoff from Beaver Stadium is set for 3:30 p.m. ET on Paramount+, where you can get a free 7-day trial. The Nittany Lions are 42.5-point favorites in the latest Nevada vs. Penn State odds from SportsLine consensus, while the over-under for total points scored is set at 54.5. Before making any Penn State vs. Nevada picks, make sure you check out the picks from the SportsLine projection model. New users at bet365 can get $200 in bonus bets instantly with the latest bet365 bonus code for Saturday’s game:
The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and was a profitable 27-16 combined on money-line and over/under college football picks in 2024. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.
Here are SportsLine model’s best bets for Nevada vs. Penn State on Saturday:
Nevada +42.5
Penn State is expected to be one of the best teams in the country, but the SportsLine projection model has Nevada keeping this game close. The Wolf Pack got some help on offense with Herschel Turner at running back, and quarterback Chubba Purdy has some experience under his belt heading into his senior year. They will still be tasked with stopping Drew Allar and an impressive Penn State offense, but the SportsLine model projects the Wolf Pack will cover in 51% of simulations.
Over 54.5
The Nittany Lions hit the Over in seven games last season. They will go up against a Nevada defense that gave up 391.5 yards per game last season, while also playing in seven games that hit the Over in 2024. The Over hits in 62% of simulations according to the SportsLine model.
Want more Week 1 college football picks?
You’ve seen the model’s best bets for Penn State vs. Nevada. Now, get against the spread, total and money-line picks for every Week 1 CFB game here, all from the model that’s simulated every game 10,000 times.
Also at SportsLine:
You can also see Week 1 college football picks from legendary college football handicapper Bruce Marshall. Visit SportsLine to see his best bets. SportsLine’s Emory Hunt, who is 45-32 in his last 77 college football picks, has locked in his best bet for Oregon State vs. California right here.
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