While No. 1 Duke, No. 1 Michigan and No. 2 Connecticut faced unexpected tests in the first round of the Men’s NCAA Tournament, the upsets on Thursday and Friday happened down the bracket, with teams from the ACC, Big Ten and Big 12 being upended by double-digit seeds.
In one of the most dramatic moments of the opening round, No. 12 High Point knocked off No. 5 Wisconsin, 83-82, on a last-second layup. In another upset, No. 11 VCU pulled off a furious comeback to beat No. 6 North Carolina, 82-78, in overtime.
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Duke made history as the only No. 1 seed to ever trail a No. 16 seed by double digits at halftime before getting back on track for a 71-65 win against Siena.
Michigan led No. 16 Howard 50-46 at halftime before its potent offense took over, turning a nailbiter into a 100-81 win. Connecticut went cold from deep in the first half against No. 15 Furman but steadied things in the second half to win 82-71.
Overall, teams on the top four lines went 16-0 in the first round with an average margin of victory of 24.5 points. Of this group, 12 won by at least 20 points, led by No. 1 Florida’s 114-55 win against No. 16 Prairie View A&M.
Let’s break down what’s happened and get ready for the weekend by examining the biggest winners and losers from the first round:
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A Texas Christian University Horned Frogs cheerleader practices before the game during a first round game of the men’s 2026 NCAA Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC.
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A Texas Christian University Horned Frogs cheerleader practices before the game during a first round game of the men’s 2026 NCAA Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC.
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Nebraska Cornhuskers fans cheer after defeating the Troy Trojans during a first round game of the men’s 2026 NCAA Tournament at Paycom Center on March 19, 2026 in Oklahoma City.
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The Ohio State Buckeyes cheerleaders perform in the second half during a first round game of the men’s 2026 NCAA Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC.
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A view of Buddy the Street Dog as Queens University of Charlotte Royals guard Yoav Berman talks to the media during a practice session ahead of the first round of the men’s 2026 NCAA Tournament at Enterprise Center in St. Louis on March 19, 2026.
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The High Point Panthers band performs prior to a first round game of the men’s 2026 NCAA Tournament against the Wisconsin Badgers at Moda Center on March 19, 2026 in Portland, Or.
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High Point Panthers fans cheer prior to a first round game of the men’s 2026 NCAA Tournament against the Wisconsin Badgers at Moda Center on March 19, 2026 in Portland, Or.
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The Wisconsin Badgers cheerleaders preform during the first half of a first round game of the men’s 2026 NCAA Tournament against the High Point Panthers at Moda Center on March 19, 2026 in Portland, Or.
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The South Florida Bulls mascot performs during the second half against the Louisville Cardinals during a first round game of the men’s 2026 NCAA Tournament at Keybank Center on March 19, 2026 in Buffalo, NY.
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The Texas Christian University Horned Frogs cheerleaders perform in the first half during a first round game of the men’s 2026 NCAA Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC.
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The Troy Trojans mascot dances on the floor during the second half against the Nebraska Cornhuskers during a first round game of the men’s 2026 NCAA Tournament at Paycom Center on March 19, 2026 in Oklahoma City.
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The UCF Knights band performs during a practice session ahead of the first round of the men’s 2026 NCAA Tournament at Xfinity Mobile Arena on March 19, 2026 in Philadelphia.
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See best of March Madness 2026, from mascots and fans to celebrities
Nebraska Cornhuskers cheerleaders perform during the second half against the Troy Trojans during a first round game of the men’s 2026 NCAA Tournament at Paycom Center on March 19, 2026 in Oklahoma City.
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A Wisconsin Badgers cheerleader performs during the first half of a first round game of the men’s 2026 NCAA Tournament against the High Point Panthers at Moda Center on March 19, 2026 in Portland, Or.
WINNERS
Nebraska
The No. 4 Cornhuskers are one of the biggest winners after rolling over No. 13 Troy, 76-47, for the program’s first tournament win. Sharpshooter Pryce Sandfort led the way with 23 points for Nebraska, which next takes on No. 5 Vanderbilt in the South region. This has been a long time coming, period, and required the patience to give coach Fred Hoiberg enough time to establish the depth and playing style that have made this the most successful team in school history.
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Saint Louis
Late on Thursday night, No. 9 Saint Louis put on a show against No. 8 Georgia to paint the Billikens as a legitimate threat to derail the Wolverines in the second round of the Midwest region. With a frantic pace and aggressive, rim-attacking approach, SLU scored 66 points in the paint and led the Bulldogs by as much as 40 points in the second half of a 102-77 win. This was particularly meaningful for coach Josh Schertz and star center Robbie Avila, who were part of the 2024 Indiana State team that was infamously snubbed as an at-large contender.
No. 9 seeds
It was a good round to be a No. 9 seed. In addition to Saint Louis, TCU beat Ohio State, 66-64, on a late bucket, Utah State beat Villanova, 86-76, and Iowa beat Clemson, 67-61. The last time No. 9 seeds went 4-0 in the first round was in 2019, when Central Florida, Baylor, Oklahoma and Washington did the honors.
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Kentucky
You shudder to think about the reaction nationally and inside its home state had No. 7 Kentucky lost to No. 10 Santa Clara – and the Wildcats seemed well on the way to doing just that until Otega Oweh’s buzzer-beating heave from just inside half court tied the game and forced overtime. From there, UK had just enough to score an 89-84 win that should temporarily quiet the frustration over an up-and-down regular season. There’s a lot of stress on the word temporarily: No. 2 Iowa State will eat the Wildcats’ lunch if they don’t step up their game before meeting on Sunday.
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See the wild game-tying 3-pointers in the Santa Clara v Kentucky NCAA game
Kentucky Wildcats guard Otega Oweh (00) shoots a three point basket against Santa Clara Broncos guard Sash Gavalyugov (2) to tie the game as time expires in the second half of a first round game of the men’s 2026 NCAA Tournament at Enterprise Center.
Oweh’s game-tying 3-pointer from near halfcourt to tie the game at 73-73 to send it to overtime. Allen Graves had hit a 3-pointer to give Santa Clara the 3-point lead after Kentucky tied it out of the timeout.
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See the wild game-tying 3-pointers in the Santa Clara v Kentucky NCAA game
Kentucky Wildcats guard Otega Oweh (00) shoots a three point basket against Santa Clara Broncos guard Sash Gavalyugov (2) to tie the game as time expires in the second half of a first round game of the men’s 2026 NCAA Tournament at Enterprise Center.
Oweh’s game-tying 3-pointer from near halfcourt to tie the game at 73-73 to send it to overtime. Allen Graves had hit a 3-pointer to give Santa Clara the 3-point lead after Kentucky tied it out of the timeout.
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See the wild game-tying 3-pointers in the Santa Clara v Kentucky NCAA game
Santa Clara Broncos forward Allen Graves (22) shoots a three point shot against Kentucky Wildcats center Malachi Moreno (24) during the second half of a first round game of the men’s 2026 NCAA Tournament at Enterprise Center.
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See the wild game-tying 3-pointers in the Santa Clara v Kentucky NCAA game
Santa Clara Broncos forward Allen Graves (22) reacts after making a basket against the Kentucky Wildcats during the second half of a first round game of the men’s 2026 NCAA Tournament at Enterprise Center.
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See the wild game-tying 3-pointers in the Santa Clara v Kentucky NCAA game
Santa Clara Broncos forward Allen Graves (22) reacts after making a basket against the Kentucky Wildcats during the second half of a first round game of the men’s 2026 NCAA Tournament at Enterprise Center.
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See the wild game-tying 3-pointers in the Santa Clara v Kentucky NCAA game
Santa Clara Broncos forward Allen Graves (22) reacts after making a basket against Kentucky Wildcats center Malachi Moreno (24) during the second half of a first round game of the men’s 2026 NCAA Tournament at Enterprise Center.
LOSERS
North Carolina
The disaster that was North Carolina’s loss to VCU threatens to change the direction of the program, given the recharged sense of unease about the state of affairs under coach Hubert Davis. While Davis did lead UNC to the national championship game in 2022 and an ACC regular-season crown in 2024, the Tar Heels’ latest first-round exit should leave Davis on a very hot seat heading into next season – or even lead to an immediate coaching change. Ahead by 19 points in the second half, UNC took its foot off the gas and allowed the Rams to chip away and force overtime before guard Terrence Hill Jr. nailed a step-back 3-pointer with 15 seconds left in the extra frame for the win.
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ACC
UNC isn’t alone amid the ACC’s disappointing start. Duke had a historic struggle but survived. Clemson lost 67-61 to Iowa. In the play-in round, No. 11 North Carolina State lost 68-66 to Texas and No. 11 SMU lost 89-79 to Miami (Ohio). On the other hand, No. 7 Miami beat No. 10 Missouri, 80-66, No. 3 Virginia beat No. 14 Wright State, 82-73, for its first tournament win since 2019 and No. 6 Louisville beat No. 11 South Florida, 83-79. The 4-4 mark so far is well off the pace of the Big 12, Big Ten and SEC, which are a combined 21-6.
West Coast Conference
On a mid-major level, no league flopped more than the West Coast. Regular-season and conference tournament champion No. 3 Gonzaga struggled in a defensive battle against No. 14 Kennesaw State but pulled out a 73-64 win. Santa Clara led Kentucky with two minutes to go, again with 1:30 to play and then made the go-ahead 3-pointer with 2.4 seconds left before Oweh delivered a miracle. And No. 7 Saint Mary’s was just pushed around and never comfortable in a 63-50 loss to No. 10 Texas A&M.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
North Carolina Tar Heels center Henri Veesaar reacts after losing to the VCU Rams in overtime of a first round game of the men’s 2026 NCAA Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
North Carolina Tar Heels center Henri Veesaar reacts after losing to the VCU Rams in overtime of a first round game of the men’s 2026 NCAA Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Brendan Coyle #21 of the Siena Saints reacts after the game against the Duke Blue Devils in the first round of the 2026 NCAA Men’s Basketball Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC. The Duke Blue Devils defeated the Siena Saints 71-65.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Head coach Kelvin Sampson of the Houston Cougars shakes hands with members of the Idaho Vandals following the first round game of the 2026 NCAA Men’s Basketball Tournament at Paycom Center on March 19, 2026, in Oklahoma City, Oklahoma.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
McNeese Cowboys guard Tyshawn Archie (8) walks off the court after losing to the Vanderbilt Commodores during a first round game of the men’s 2026 NCAA Tournament at Paycom Centeron March 19, 2026 in Oklahoma City.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Riley Saunders #13 and Andy Stefonowicz #5 of the North Dakota State Bison high five after being defeated by the Michigan State Spartans in the first round of the 2026 NCAA Men’s Basketball Tournament at KeyBank Center on March 19, 2026 in Buffalo, New York.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Wisconsin Badgers guard Braeden Carrington (0) and guard John Blackwell (25) react during the second half of a first round game of the men’s 2026 NCAA Tournament against the High Point Panthers at Moda Center on March 19, 2026 in Portland, Or.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Thomas Dowd of the Troy Trojans reacts after coming out of the game against the Nebraska Cornhuskers during the second half in the first round of the 2026 NCAA Men’s Basketball Tournament at Paycom Center on March 19, 2026 in Oklahoma City, Okla.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Ohio State Buckeyes forward Amare Bynum (1) and Ohio State Buckeyes forward Brandon Noel (14) react after losing to Texas Christian University Horned Frogs during a first round game of the men’s 2026 NCAA Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Texas Christian University Horned Frogs forward Xavier Edmonds (24) reacts after defeating the Ohio State Buckeyes during a first round game of the men’s 2026 NCAA Tournament at Bon Secours Wellness Arena on March 19, 2026 in Greenville, SC.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Lehigh Mountain Hawks huddle together after being defeated by the Prairie View A&M Panthers during a first four game of the men’s 2026 NCAA Tournament at University of Dayton Arena on March 18, 2026.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
SMU Mustangs guard Boopie Miller (2) and SMU Mustangs center Jaden Toombs (10) leave the court after being defeated by the Miami (OH) RedHawks during a first four game of the men’s 2026 NCAA Tournament at University of Dayton Arena on March 18, 2026.
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March Sadness hits hard in the NCAA Men’s Basketball Tournament
Trevon Blassingame #1 and Seth Joba #21 of the Idaho Vandals react after the defeat against the Houston Cougars in the first round of the 2026 NCAA Men’s Basketball Tournament at Paycom Center on March 19, 2026, in Oklahoma City, Oklahoma.
Brigham Young
This entire season was a bit of a flop given the hype around BYU and freshman star AJ Dybantsa, even if Dybantsa matched all expectations with a banner one-and-done year. The No. 6 Cougars’ year ended with a 79-71 loss to No. 11 Texas that pretty much sum that up: Dybantsa scored 35 points and had 10 rebounds, though he did turn the ball over five times and make just 1 of 7 attempts from deep.
This article originally appeared on USA TODAY: Winners and losers of first round of Men’s NCAA Tournament