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Its Friday, April 18 and the Guardians (9-9) are in Pittsburgh to take on the Pirates (8-12).

Luis L. Ortiz is slated to take the mound for Cleveland against Carmen Mlodzinski for Pittsburgh.

Cleveland has lost two in a row and three of their last four. Last night they lost 6-2 to the Orioles. Tanner Bibee gave up all six runs in 5.2 innings. Meanwhile, the Pirates have won two in a row and three of their last four. Yesterday, Andrew Heaney was spectacular throwing 7.1 shutout innings as the Bucs took down the Nationals, 1-0.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Guardians at Pirates

  • Date: Friday, April 18, 2025
  • Time: 6:40PM EST
  • Site: PNC Park
  • City: Pittsburgh, PA
  • Network/Streaming: CLEG, SNP

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Guardians at the Pirates

The latest odds as of Friday:

  • Moneyline: Guardians (-121), Pirates (+102)
  • Spread: Guardians -1.5
  • Total: 8.0 runs

Probable starting pitchers for Guardians at Pirates

  • Pitching matchup for April 18, 2025: Luis L. Ortiz vs. Carmen Mlodzinski
    • Guardians: Luis L. Ortiz (1-2, 6.06 ERA)
      Last outing: 4/12 vs. Kansas City – 5.2IP, 1ER, 1H, 2BB, 10Ks
    • Pirates: Carmen Mlodzinski (1-2, 6.23 ERA)
      Last outing: 4/13 at Cincinnati – 4.1IP, 4ER, 5H, 2BB, 4Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Guardians at Pirates

  • The Guardians have a 5-1 record in series openers this season
  • 4 of the Pirates’ last 5 home games stayed under the Total
  • The Guardians have failed to cover the Run Line in 7 of their last 9 road games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Guardians and the Pirates

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Friday’s game between the Guardians and the Pirates:

  • Moneyline: NBC Sports Bet is recommending a play on the Cleveland Guardians on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Pittsburgh Pirates at +1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)



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