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The No. 15 Alabama Crimson Tide (5-2) will try to keep their College Football Playoff hopes alive when they host the No. 21 Missouri Tigers (6-1) on Saturday afternoon. Alabama has lost two of its last three games, falling to Vanderbilt as a heavy favorite at the beginning of the month and to then-No. 11 Tennessee last week. Missouri is riding a two-game winning streak following its loss to then-No. 25 Texas A&M, notching a 21-17 win against Auburn last week. This is the first meeting between these teams since Alabama picked up a 38-19 win in 2020. 

Kickoff is set for 3:30 p.m. ET on Saturday at Bryant-Denny Stadium. Alabama is favored by 16.5 points in the latest Alabama vs. Missouri odds, while the over/under is 51 points, per SportsLine consensus. Before entering any Missouri vs. Alabama picks, you’ll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 14-7 on all top-rated picks over the past four weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.

The model has set its sights on Missouri-Alabama. You can head to SportsLine to see its picks. Here are several college football betting lines for the game:

  • Alabama vs. Missouri spread: Alabama -16.5
  • Alabama vs. Missouri over/under: 51 points
  • Alabama vs. Missouri money line: Alabama -833, Missouri +557
  • Alabama vs. Missouri picks: See picks here
  • Alabama vs. Missouri streaming: FuboTV (Try for free)

Why Alabama can cover

Alabama has no margin for error if it wants to make the 12-team College Football Playoff this season, as it has dropped two of its last three games to teams from the state of Tennessee. The Crimson Tide should come out with a motivated effort on Saturday, and they still have one of the most talented rosters in the country. Junior quarterback Jalen Milroe has completed 68.4% of his passes for 1,722 yards and 13 touchdowns while rushing for 330 yards and 11 more scores. 

Junior running back Jam Miller leads the rushing attack with 402 yards and five touchdowns, averaging 6.4 yards per carry. Star freshman wide receiver Ryan Williams has 31 receptions for 649 yards and seven touchdowns, while junior Germie Bernard is the second-leading receiver with 25 catches for 381 yards. Alabama is riding a nine-game home winning streak. See which team to pick here. 

Why Missouri can cover

Alabama has looked extremely shaky since its win over Georgia at the end of September, starting with an outright loss to Vanderbilt as a 23-point favorite. The Crimson Tide barely snuck past South Carolina in their following game, despite entering that contest as 21.5-point favorites. They proceeded to lose to Tennessee last week as 3.5-point favorites, so they are not in good form right now. 

Missouri has covered the spread in back-to-back games since its lone loss of the season three weeks ago, cruising to a blowout win at UMass before beating Auburn last week. Senior quarterback Brady Cook returned mid-game from an MRI on his ankle to lead a pair of fourth-quarter touchdown drives in the win over Auburn. The Tigers have covered the spread in 13 of their last 18 games, and they have covered in five of their last six road games. See which team to pick here. 

How to make Alabama vs. Missouri picks

The model has simulated Missouri vs. Alabama 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits well over 50% of the time. You can only see the pick at SportsLine.

So who wins Alabama vs. Missouri, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Missouri vs. Alabama spread to jump on, all from the advanced computer model that’s up well over $2,000 on its top-rated college football spread picks since its inception, and find out.



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