Its Monday, October 6 and baseball’s playoffs continue as the Cubs (92-70) are in Milwaukee to take on the Brewers (97-65) in Game 2 of their National League Division Series. Shota Imanaga is slated to take the mound for Chicago against Aaron Ashby for Milwaukee.
The Brewers lead the best-of-five series 1-0 following Saturday’s series-opening 9-3 win. Jackson Chourio sparked the attack from the leadoff spot with three hits in three at bats and drove in three runs. However, Chourio aggravated his right hamstring over the course of the game, and his availability is a question mark for tonight’s game. Freddy Peralta picked up the win in Game 1 allowing two runs over 5.2 innings while striking out nine. Matthew Boyd took the loss giving up six runs (two earned) and did not make it out of the first inning.
Shota Imanaga took the loss in Game 2 of the Wild Card series against the Padres allowing two runs over four innings. Aaron Ashby pitched 1.1 scoreless innings in Game 1. While the Cubs are counting on an extended outing from Imanaga, the Brewers will be content with two innings from Ashby who rarely pitched into a third inning (6 times) over 45 regular season appearances.
Lets dive into Game 2 and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Cubs at Brewers
- Date: Monday, October 6, 2025
- Time: 9:08PM EST
- Site: American Family Field
- City: Milwaukee, WI
- Network/Streaming: TBS, truTV, HBO Max
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Odds for the Cubs at the Brewers – NLDS Game 2
The latest odds as of Monday courtesy of DraftKings:
- Moneyline: Chicago Cubs (+105), Milwaukee Brewers (-127)
- Spread: Brewers -1.5 (+160)
- Total: 7.5 runs
Probable starting pitchers for Cubs at Brewers
- Pitching matchup for October 6, 2025: Shota Imanaga vs. Aaron Ashby
- Cubs: Shota Imanaga (Regular Season: 9-8, 3.73 ERA)
Last outing: 10/1 vs. San Diego – 4IP, 4.50 ERA, 2 Earned Runs Allowed, 3 Hits, 2 BBs, and 3 Ks - Brewers: Aaron Ashby (Regular Season: (0-0, 2.16 ERA, 3 Saves)
Last outing: 10/4 vs. Cubs – 1.1 IP, 0.00 ERA, 0 Earned Runs Allowed, 0 Hits, 0 BBs, and 1 K
- Cubs: Shota Imanaga (Regular Season: 9-8, 3.73 ERA)
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Top betting trends & insights to know ahead of Cubs at Brewers – NLDS Game 2
- Ian Happ is 3-10 with 1 HR lifetime against Aaron Ashby
- Dansby Swanson is 3-7 lifetime against Aaron Ashby
- William Contreras is 3-10 with 2 HRs in his career against Shota Imanaga
- Christian Yelich is 3-10 with 1 HR in his career against Shota Imanaga
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s Game 2 between the Cubs and the Brewers
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Monday’s Game 2 between the Cubs and the Brewers:
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago Cubs at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 7.5.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page fromNBC
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