The No. 8 Florida State Seminoles travel to face the Virginia Cavaliers in a key ACC matchup on Friday. FSU has opened year six under head coach Mike Norvell with a 3-0 record, winning each game by at least 14 points. Transfer quarterback Tommy Castellanos has emerged as a dynamic playmaker, energizing Florida State’s offense. Virginia enters the game 3-1 overall and 1-0 in conference play, coming off a commanding 38-20 victory over Stanford on Sept. 20. Running back J’Mari Taylor has been a key contributor for the Cavaliers, providing a consistent rushing threat and helping anchor Virginia’s outstanding ground game. Both teams have seen success against the spread this season, with Florida State sitting at 3-0 and Virginia at 3-1.
Kickoff from Scott Stadium in Charlottesville, Virg. is set for 7 p.m. ET. The Seminoles are 7-point favorites in the latest Virginia vs. Florida State odds, while the over/under for total points scored is 60.5. Before making any Florida State vs. Virginia picks, make sure you check out what SportsLine college football expert Jimmie Kaylor has to say.
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Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years.
Kaylor has destroyed the sportsbooks in college football the last two seasons, posting a 242-166-7 record since Week 1 of the 2023 season. His 2024 college football futures picks included Travis Hunter winning the Heisman at 40-1 odds, bringing his net profit up to a whopping 103.81 units ($10,381.50 for a $100 bettor) since joining SportsLine as an expert in 2023.
All of his picks have been featured on his SportsLine expert page or in his weekly bylined articles. Anyone who followed his picks could be way up.
Now, Kaylor has zoned in on Virginia vs. Florida State and just locked in his picks and CFB predictions. You can head to SportsLine now to see his picks. Here are several college football odds and college football betting lines for FSU vs. Virginia:
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Florida State vs. Virginia spread |
Florida State -7 at DraftKings Sportsbook |
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Florida State vs. Virginia over/under |
60.5 points |
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Florida State vs. Virginia money line |
Florida State -265, Virginia +215 |
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Florida State vs. Virginia picks |
See picks at SportsLine |
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Florida State vs. Virginia streaming |
Fubo (Try for free) |
Why Florida State can cover
The Noles have emerged as one of the most dominant teams in college football early in the 2025 season. Under guidance of first-year offensive coordinator Gus Malzahn, the Noles are averaging an impressive 58 points per game. Quarterback Tommy Castellanos has been a standout, throwing for 594 yards, three touchdowns, and one interception, while also rushing for 139 yards and three scores on the ground.
The offense’s success is further bolstered by wide receiver Micahi Danzy, who leads the team with 173 rushing yards to go with 126 receiving yards, and Duce Robinson, who leads the team in receptions (8), receiving yards (199), and touchdown receptions (2). On the defensive side, Earl Little Jr. has been a key contributor, leading the team with 15 tackles, while Jerry Wilson has made his presence felt in the secondary with two interceptions. See which team to back at SportsLine.
Why Virginia can cover
The Cavaliers have made significant strides under fourth-year head coach Tony Elliott. The Wahoos enter this matchup at 3-1 overall, with a 1-0 record in conference play. The Virginia offense has been explosive in 2025, averaging 556 total yards per game.
Quarterback Chandler Morris has thrown for 1,050 passing yards, eight touchdowns, and one interception. He’s also rushed for 132 yards and one touchdown. Senior running back J’Mari Taylor leads the team with 298 rushing yards and six touchdowns. Wide receiver Trell Harris has also been a key contributor, leading the team with 321 receiving yards and three touchdowns. See which team to back at SportsLine.
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How to make Florida State vs. Virginia picks
For Friday’s FSU vs. Virginia matchup, Kaylor is leaning Over on the point total, but he also says a critical X-factor makes one side of the spread a must-back. You can only see what it is, and which side to back, at SportsLine.
Who covers in Virginia vs. Florida State, and what critical x-factor do you need to know about? Visit SportsLine now to see which side of the Florida State vs. Virginia spread you need to jump, all from the expert who returned $10,382 to $100 players since the start of the 2023 season, and find out.
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