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Its Wednesday, June 25 and the Phillies (47-32) are in Houston to take on the Astros (46-33).

Zack Wheeler is slated to take the mound for Philadelphia against Colton Gordon for Houston in Game 2 of this series featuring first place clubs.

Coper Hummel spoiled an old-fashioned pitchers’ duel last night with a solo home run in the bottom of the eighth inning as the Astros won, 1-0. Framber Valdez combined with Bryan Abreu and Josh Hader on the four-hit shutout of the Phillies.

Lets dive into tonight’s matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Phillies at Astros

  • Date: Wednesday, June 25, 2025
  • Time: 8:10PM EST
  • Site: Minute Maid Park
  • City: Houston, TX
  • Network/Streaming: NBCSP, SCHN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Phillies at the Astros

The latest odds as of Wednesday:

  • Moneyline: Phillies (-162), Astros (+135)
  • Spread: Phillies -1.5
  • Total: 7.0 runs

Probable starting pitchers for Phillies at Astros

  • Pitching matchup for June 25, 2025: Zack Wheeler vs. Colton Gordon
    • Phillies: Zack Wheeler (7-2, 2.61 ERA)
      Last outing: 6/20 vs. Mets – 5IP, 0ER, 4H, 3BB, 8Ks
    • Astros: Colton Gordon (2-1, 4.54 ERA)
      Last outing: 6/19 at Athletics – 5IP, 2ER, 7H, 1BB, 4Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Phillies at Astros

  • The Phillies have won 7 of their last 10 games
  • 6 of the Phillies’ last 7 road games stayed under the Total
  • The Astros have failed to cover the Run Line in 5 straight games
  • Jose Altuve is just 1-15 over his last 5 games
  • Alec Bohm is hitting .333 in June (27-81)

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Phillies and the Astros

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Phillies and the Astros:

  • Moneyline: NBC Sports Bet is recommending a play on the Philadelphia Phillies on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Philadelphia Phillies -1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 7.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)



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