Its Friday, May 23 and the Diamondbacks (26-24) are in St. Louis to take on the Cardinals (27-23).
Zac Gallen is slated to take the mound for Arizona against Miles Mikolas for St. Louis.
Both St. Louis and Arizona were off Thursday. Each is coming off a series that saw them drop two of three. The Cards lost two to the Tigers including a 5-1 loss Wednesday. Arizona lost the final two of their series against the Dodgers.
Lets dive into the matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game details & how to watch Diamondbacks at Cardinals
- Date: Friday, May 23, 2025
- Time: 8:15PM EST
- Site: Busch Stadium
- City: St. Louis, MO
- Network/Streaming: Apple TV+
Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.
Odds for the Diamondbacks at the Cardinals
The latest odds as of Thursday:
- Moneyline: Diamondbacks (-129), Cardinals (+109)
- Spread: Diamondbacks -1.5
- Total: 8.0 runs
Probable starting pitchers for Diamondbacks at Cardinals
- Pitching matchup for May 23, 2025: Zac Gallen vs. Miles Mikolas
- Diamondbacks: Zac Gallen (3-5, 5.14 ERA)
Last outing: 5/17 vs. Colorado – 5IP, 6ER, 8H, 2BB, 5Ks - Cardinals: Miles Mikolas (3-2, 3.77 ERA)
Last outing: 5/17 at Kansas City – 6IP, 0ER, 2H, 2BB, 4Ks
- Diamondbacks: Zac Gallen (3-5, 5.14 ERA)
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Top betting trends & insights to know ahead of Diamondbacks at Cardinals
- Betting the Diamondbacks on the Money Line in all their road games this season is showing a 106% return on investment
- The Under has cashed in 5 of the Cardinals’ last 7 games with Miles Mikolas on the mound
- The Cardinals have covered in 4 successive games with Miles Mikolas as the starter
- Willson Contreras is 3-19 over his last 5 games
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!
Expert picks & predictions for tonight’s game between the Diamondbacks and the Cardinals
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Friday’s game between the Diamondbacks and the Cardinals:
- Moneyline: NBC Sports Bet is recommending a play on the Arizona Diamondbacks on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the St. Louis Cardinals at +1.5.
- Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.
Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC
Follow our experts on socials to keep up with all the latest content from the staff:
- Jay Croucher (@croucherJD)
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- Vaughn Dalzell (@VmoneySports)
- Brad Thomas (@MrBradThomas)
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