Conference battles heat up during the Week 4 college football schedule. One of the headliners is Illinois vs. Indiana (-6), while Michigan vs. Nebraska (+2.5) and USC vs. Michigan State (+18.5) also unfold in the Big Ten. Utah vs. Texas Tech (+3.5) is the top Big 12 matchup, while the SEC features Oklahoma vs. Auburn (+7) and South Carolina vs. Missouri (-11.5).
There are some intriguing non-conference games between in-state rivals as well as Notre Dame vs. Purdue (+25.5), Oregon vs. Oregon State (+35.5), Florida vs. Miami (+7.5) and Washington vs. Washington State (+19.5) also on the slate. Which Week 4 college football odds bring the most value? Before locking in any Week 4 college football picks on those game or others, be sure to see the top Week 4 college football expert picks, predictions and best bets from Thomas Casale.
A frequent guest on national radio and TV shows to discuss college sports, Casale has been sports betting — and winning — for more than 30 years. After going 6-5 so far this season, he’s on a 19-11 roll in his SportsLine best bets column that dates back to last season. Anybody who followed him could have been way up.
Now, he has turned his attention to the Week 4 college football odds and is sharing his top betting picks. If you parlay these college football betting picks, you could be looking at a return of around +600. Get his top college football picks at SportsLine.
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Top Week 4 college football expert predictions
One of Casale’s top Week 4 college football picks: He is backing No. 21 Michigan on the money line (-135) at Nebraska in a 3:30 p.m. ET kickoff on CBS and Paramount+ (plans start at $30 for one year) on Saturday.
“One thing I think is interesting heading into this matchup is we saw Bryce Underwood run more last week against Central Michigan, finishing with nine carries for 114 yards. Underwood averaged just two rushing attempts per game in high school and carried the ball five times in the first two weeks. Underwood using his legs more makes Michigan’s offense tougher to defend and it should help the true freshman feel more comfortable in his second career road start. He struggled at Oklahoma, although the Sooners have one of the top defenses in the country.
“Nebraska quarterback Dylan Raiola has struggled with turnovers in the past and that could be an issue again on Saturday versus an aggressive Michigan defense. The Cornhuskers hammered two creampuffs but played a close game with Cincinnati in the opener, winning 20-17. I don’t have the Bearcats rated very high in my power rankings, so I’m still not sold on Nebraska’s offense. I like the Wolverines to leave Lincoln with a hard-fought win.” See what other picks Casale likes at SportsLine.
How to make Week 4 college football picks
Casale has found two other college football picks he loves, including backing an underdog in a game where he says the wrong team is favored. You can only see his picks at SportsLine, and you can use promo code CHAMPIONSHIP to get your first month at SportsLine for just $1.
What are the best bets for Week 4 of college football, and which underdog does Casale believe will win outright? Visit SportsLine now to see Thomas Casale’s college football best bets, all from a proven college football handicapper who is on an 19-11 roll on CFB best bets, and find out.
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